EMBO Workshop on piRNAs and PIWI proteins - Maison Des Choeurs


The piRNA pathway is an RNA-silencing pathway involving small non-coding RNAs and specific Argonaute proteins, the PIWI proteins. This pathway was discovered a decade ago as a defense mechanism against transposons. The field is progressing rapidly and in recent years, studies on piRNAs have broadened from transposable element regulation to post-transcriptional gene regulation, roles in stem cell biology, and in somatic tissues and cancer biology. The aim of this EMBO Workshop is to discuss the latest findings on all the different aspects of piRNA biology, and thus to cover the entire field. There will be a particular focus to support scientists in early career stages to foster discussions and collaborations. This workshop is the second of the EMBO Workshop series specifically dedicated to piRNA biology.

Topics include:

piRNA biogenesis
piRNAs/PIWI proteins in genome defense
epigenetic regulation
regulation of endogenous gene expression programs
stem cell biology
genome rearrangements
somatic tissues and cancer

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